Zhao, Hong, Tombola, et al. leverage the analysis of local conformational changes in a mutant Hv1 channel to inform the design of new inhibitors (https://t.co/d4jan1xjGg). Part of our collection on #Protons and #Membrane Function: https://t.co/OomFZXR1…
Chang Zhao, Liang Hong, Francesco Tombola et al @UCIrvine design new arginine mimic inhibitors of Hv1 channels that have improved interaction with the voltage-sensing domain and inhibit the wild-type channel with higher strength than guanidine derivativ…
RT @JGenPhysiol: HIFs: New arginine mimic inhibitors of the Hv1 channel with improved VSD–ligand interactions. New study from Chang Zhao, L…
HIFs: New arginine mimic inhibitors of the Hv1 channel with improved VSD–ligand interactions. New study from Chang Zhao, Liang Hong, Francesco Tombola and colleagues @UCIrvine. https://t.co/d4jan1xjGg #Biophysics #MembraneTransport #MolecularPharmacology…