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Prevalent Glucocorticoid and Androgen Activity in US Water Sources

Overview of attention for article published in Scientific Reports, December 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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6 X users
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3 patents

Citations

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51 Dimensions

Readers on

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52 Mendeley
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Title
Prevalent Glucocorticoid and Androgen Activity in US Water Sources
Published in
Scientific Reports, December 2012
DOI 10.1038/srep00937
Pubmed ID
Authors

Diana A. Stavreva, Anuja A. George, Paul Klausmeyer, Lyuba Varticovski, Daniel Sack, Ty C. Voss, R. Louis Schiltz, Vicki S. Blazer, Luke R. Iwanowicz, Gordon L. Hager

Abstract

Contamination of the environment with endocrine disrupting chemicals (EDCs) is a major health concern. The presence of estrogenic compounds in water and their deleterious effect are well documented. However, detection and monitoring of other classes of EDCs is limited. Here we utilize a high-throughput live cell assay based on sub-cellular relocalization of GFP-tagged glucocorticoid and androgen receptors (GFP-GR and GFP-AR), in combination with gene transcription analysis, to screen for glucocorticoid and androgen activity in water samples. We report previously unrecognized glucocorticoid activity in 27%, and androgen activity in 35% of tested water sources from 14 states in the US. Steroids of both classes impact body development, metabolism, and interfere with reproductive, endocrine, and immune systems. This prevalent contamination could negatively affect wildlife and human populations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Mexico 1 2%
Unknown 49 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 23%
Student > Bachelor 8 15%
Student > Ph. D. Student 7 13%
Student > Master 7 13%
Other 3 6%
Other 7 13%
Unknown 8 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 37%
Environmental Science 8 15%
Biochemistry, Genetics and Molecular Biology 6 12%
Engineering 6 12%
Earth and Planetary Sciences 2 4%
Other 3 6%
Unknown 8 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2018.
All research outputs
#3,296,174
of 24,171,551 outputs
Outputs from Scientific Reports
#27,862
of 131,471 outputs
Outputs of similar age
#32,787
of 285,944 outputs
Outputs of similar age from Scientific Reports
#75
of 296 outputs
Altmetric has tracked 24,171,551 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 131,471 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.6. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,944 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 296 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.