In total, @GWASCatalog lists 79 studies with genome-wide significant hits for SLC2A9 and uric acid! The strongest p-value reported in the gwas catalog is 1e-700, but this is incorrect. Yes, I get to mention my favorite pet peeve around underflow. https:…
Hey @GWASCatalog - while checking on associations with neglogp=300, please also check out rs12498742 for uric acid. Listed as neglogp = 700. I calculate neglogp=842. https://t.co/zTimAexT3d Would be easier if @GWASCatalog didn't round beta, standard err…
@manuelrivascruz SLC22A11 is a kidney-specific solute transporter, associated previously with urate levels: https://t.co/zTimAexT3d The hit on chromosome 4 (WDR1) is undoubtedly tagging or influencing SLC2A9, another kidney-specific solute transporter w…
次回の論文発表は自分の遺伝子的にリスク高めな痛風のGWAS取り上げよう... と思ってざっと眺めたらめっちゃ長くて著者名だけで5pある Nature Genetics : http://t.co/kbVyUd7oQx