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Immunostimulatory in Vitro and in Vivo Effects of a Water-Soluble Extract from Kale

Overview of attention for article published in Nippon Nōgeikagaku Kaishi, May 2014
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Title
Immunostimulatory in Vitro and in Vivo Effects of a Water-Soluble Extract from Kale
Published in
Nippon Nōgeikagaku Kaishi, May 2014
DOI 10.1271/bbb.100490
Pubmed ID
Authors

Kosuke NISHI, Ai KONDO, Takeaki OKAMOTO, Hiroyuki NAKANO, Miho DAIFUKU, Sogo NISHIMOTO, OCHI Kenji, Terumi TAKAOKA, Takuya SUGAHARA

Abstract

The water-soluble fraction of kale (Brassica oleracea L. var. acephala DC.) had immunoglobulin (Ig) production stimulating activity in human hybridoma HB4C5 cells and human peripheral blood lymphocytes. The biochemical and physical properties of the main active substance in kale were found to be a heat-stable protein with a molecular weight higher than 50 kDa. The Ig production-stimulating factors were assumed to act on the translational and/or secreting processes of Igs. This Ig production-stimulating effect was also observed in lymphocytes from the mesenteric lymph node and Peyer's patches of mice that had been administered with the kale extract for 14 d. The partially purified kale extract was analyzed by LC-ESI-MS/MS, the result indicating ribulose-1,5-bisphosphate carboxylase/oxygenase (rubisco) as an active substance. Rubisco from spinach indeed exhibited Ig production-stimulating activity in HB4C5 cells. These findings provide another beneficial aspect of kale as a health-promoting foodstuff.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 18%
Researcher 3 14%
Student > Bachelor 3 14%
Student > Master 2 9%
Student > Doctoral Student 1 5%
Other 5 23%
Unknown 4 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 45%
Medicine and Dentistry 2 9%
Nursing and Health Professions 2 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Other 2 9%
Unknown 4 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2023.
All research outputs
#20,331,121
of 25,850,671 outputs
Outputs from Nippon Nōgeikagaku Kaishi
#6,539
of 7,190 outputs
Outputs of similar age
#168,759
of 240,956 outputs
Outputs of similar age from Nippon Nōgeikagaku Kaishi
#2,677
of 2,823 outputs
Altmetric has tracked 25,850,671 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,190 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,956 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2,823 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.