| Title |
Fetal asphyctic preconditioning modulates the acute cytokine response thereby protecting against perinatal asphyxia in neonatal rats
|
|---|---|
| Published in |
Journal of Neuroinflammation, January 2013
|
| DOI | 10.1186/1742-2094-10-14 |
| Pubmed ID | |
| Authors |
Evi Vlassaks, Eveline Strackx, Johan SH Vles, Maria Nikiforou, Pilar Martinez-Martinez, Boris W Kramer, Antonio WD Gavilanes |
| Abstract |
Perinatal asphyxia (PA) is a major cause of brain damage and neurodevelopmental impairment in infants. Recent investigations have shown that experimental sublethal fetal asphyxia (FA preconditioning) protects against a subsequent more severe asphyctic insult at birth. The molecular mechanisms of this protection have, however, not been elucidated. Evidence implicates that inflammatory cytokines play a protective role in the induction of ischemic tolerance in the adult brain. Accordingly, we hypothesize that FA preconditioning leads to changes in the fetal cytokine response, thereby protecting the newborn against a subsequent asphyctic insult. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 23% |
| Student > Master | 4 | 18% |
| Researcher | 3 | 14% |
| Professor | 3 | 14% |
| Other | 1 | 5% |
| Other | 2 | 9% |
| Unknown | 4 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 27% |
| Computer Science | 2 | 9% |
| Neuroscience | 2 | 9% |
| Sports and Recreations | 2 | 9% |
| Medicine and Dentistry | 2 | 9% |
| Other | 2 | 9% |
| Unknown | 6 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2013.
All research outputs
#18,326,065
of 22,693,205 outputs
Outputs from Journal of Neuroinflammation
#2,053
of 2,611 outputs
Outputs of similar age
#218,250
of 281,533 outputs
Outputs of similar age from Journal of Neuroinflammation
#22
of 31 outputs
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