Congratulations, great paper! But what makes you think that this is a CARD and not just any death-fold domain? pyrin and DEDs can also activate caspases and invertebrates use all kinds of death-fold domains for that purpose! I don't think this one reall…
We previously showed that bacteria encode the pore-forming protein gasdermin and that it defends against phage infection https://t.co/bnIAyYlqQK BUT the mechanism by which the gasdermin system defends bacteria against phage remained unknown.
We previously showed that bacteria encode the pore-forming protein gasdermin and that it defends against phage infection https://t.co/bnIAyYlqQK BUT the mechanism by which the gasdermin system defends bacteria against phage remained unknown.
Is this... an intentional pun? https://t.co/IoUviKbeO9 https://t.co/oRjW4Poquf