Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia

Overview of attention for article published in Journal of Clinical Investigation, September 2016

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In the top 25% of all research outputs scored by Altmetric
High Attention Score compared to outputs of the same age (87th percentile)
Above-average Attention Score compared to outputs of the same age and source (59th percentile)

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twitter: 14 X users
patent: 19 patents

facebook: 2 Facebook pages

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mendeley: 111 Mendeley

So far, Altmetric has seen 19 patents that reference this research output.

Protein tyrosine kinase 6 (PTK6) degradation / disruption compounds and methods of use

Grant US-12678507-B2

United States of America

14 Jul 2026

Substituted nucleoside analogs as PRMT5 inhibitors

Grant US-12673054-B2

United States of America

07 Jul 2026

Heterobifunctional compounds as degraders of HPK1

Grant US-12465648-B2

United States of America

11 Nov 2025

PRMT5 inhibitors

Grant US-12391695-B2

United States of America

19 Aug 2025

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