Base-specific sequences that bias somatic hypermutation deduced by analysis of out-of-frame human IgVH genes.

Overview of attention for article published in The Journal of Immunology, March 1998

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Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g.

Сомати́ческая гипермута́ция — один из молекулярных механизмов, обеспечивающих разнообразие антител.

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