Reconfigurable asymmetric protein assemblies through implicit negative design

Overview of attention for article published in Science, January 2022

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設計技術的にはScience 2022 https://t.co/Thy3F12FaY × Nature 2024 https://t.co/wpiloW3FEr という感じ。

@adam_broerman This project builds on our previous work on protein switches, switchable assemblies, and exchanging protein assemblies: https://t.co/75ml4dqN07 https://t.co/cnzTvQ2vCe https://t.co/1GTSEzxSLp

@Reubensbrews @RavennaBrewing We used Will Sheffler's WORMS tool (https://t.co/mUhWINmo9C) to connect our previously designed hinge proteins (https://t.co/htaa4kp3At) with our previously designed reversible heterodimers (https://t.co/djxbQhLa9W).

Design of complicated all-α protein structures https://t.co/vHmFn7s3HP Reconfigurable asymmetric protein assemblies through implicit negative design https://t.co/Thy3F12FaY Design of protein-binding proteins from the target structure alone https://t.co/…

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