An Optimized Synthesis of Fmoc‑l‑Homopropargylglycine-OH

Overview of attention for article published in Journal of Organic Chemistry, February 2022

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Recent paper from our group; many congratulations @polym0n An Optimized Synthesis of Fmoc-l-Homopropargylglycine-OH https://t.co/9QIsVGDSaG

Want to make a clickable peptide without spending $1k/g on an alkynyl AA? I’m glad to report this synthesis of Fmoc-L-HPG-OH, 72% over 5 steps starting with Boc-L-Glu-OtBu and maintaining 99% ee! https://t.co/KIMgN9BhVT

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