@Amanda_Jodeh @CapitalistFraud @awaisaftab @ProfRobHoward @tillytog01 @GeorgeKirov1 @SashaGusevPosts Additionally, the use of high-coverage and deep-sequencing whole-genome sequencing (WGS) is necessary due to the inherent limitations of traditional GWA…
@FdeWzeQ @rednight0115 哦对了。在Weiner et al (2023）的评估当中基本上发现了罕见变异的极小贡献。 https://t.co/gNwQGWyeS9 但是其它文献基本上发现了罕见变异在复杂性状当中的极大贡献。例如Pierrick Wainschtein et al （2022） https://t.co/qKpoTZg2vE Weiner et…
Wainschtein, P., Jain, D., Zheng, Z., Cupples, L. A., Shadyab, A. H., McKnight, B., ... & Visscher, P. M. (2022). Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. Nature genetics, 54(3), 263-…
RT @AlexTISYoung: @Luke0connor @NadigAjay @SashaGusevPosts @ShaiCarmi I would have guessed under 50%, but looking again at the Gazal et al.…