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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Finally, An Apoptosis-Targeting Therapeutic for Cancer
|
|---|---|
| Published in |
Cancer Research, October 2016
|
| DOI | 10.1158/0008-5472.can-16-1248 |
| Pubmed ID | |
| Authors |
Carlo M Croce, John C Reed |
| Abstract |
Resistance to cell death represents one of the hallmarks of cancer. Various genetic and epigenetic changes in malignant cells afford cytoprotection in the face of genomic instability, oncogene activation, microenvironment stress, chemotherapy, targeted anticancer drugs, and even immunotherapy. Central among the regulators of cell life and death are Bcl-2 family proteins, with the founding member of the family (B-cell lymphoma/leukemia-2) discovered via its involvement in chromosomal translocations in lymphomas. The quest for therapeutics that target cell survival protein Bcl-2 represents a long road traveled, with many dead-ends, disappointments, and delays. Finally, a Bcl-2-targeting medicine has gained approval as a new class of anticancer agent. Cancer Res; 76(20); 1-7. ©2016 AACR. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 33% |
| India | 1 | 17% |
| Chile | 1 | 17% |
| Pakistan | 1 | 17% |
| Unknown | 1 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 140 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 30 | 21% |
| Student > Ph. D. Student | 28 | 20% |
| Student > Bachelor | 22 | 15% |
| Researcher | 12 | 8% |
| Student > Master | 12 | 8% |
| Other | 11 | 8% |
| Unknown | 28 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 49 | 34% |
| Agricultural and Biological Sciences | 27 | 19% |
| Medicine and Dentistry | 10 | 7% |
| Chemistry | 6 | 4% |
| Engineering | 5 | 3% |
| Other | 14 | 10% |
| Unknown | 32 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2022.
All research outputs
#2,299,340
of 23,269,984 outputs
Outputs from Cancer Research
#1,739
of 18,047 outputs
Outputs of similar age
#41,547
of 320,775 outputs
Outputs of similar age from Cancer Research
#52
of 188 outputs
Altmetric has tracked 23,269,984 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 18,047 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,775 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 188 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.