Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

Overview of attention for article published in Nature Communications, March 2022

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RT @XianyongYin: Glad our paper is highlighted by IGES @genepisociety. Thanks to collaborators @Eric_Fauman @klmohlke and many others not o…

I put CERS6 on Chr2 in italics because it is not actually in the EGEA. Not for lack of evidence but because we didn't report that locus in Yin et al because while it reached genome-wide significance (5e-8) it didn't reach study-wide significance (7.2e-1…

So this hit for glycerol-3-phosphate at GPD2 wasn't reported in Yin et al. But is it real? https://t.co/kg0hv9nxEa

This GWAS comes from the METSIM genetics metabolomics study of 1391 metabolites in 6136 men. Because of the large number of endpoints we set a significance threshold of 7.2e-11. This GWAS only gets to 6.7e-9: "genome wide significant" but not "study wid…

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