Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

Overview of attention for article published in Nature Genetics, March 2022

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@johnbind2 @SashaGusevPosts @sentientist Or, take Educational attainment: 2022 GWAS produced a polygenic predictor explaining ~12–16% of individual variation in European-ancestry samples, but within-family analyses indicated that only ~half of its associa…

Key papers from SSGAC: Lee et al. 2018 (Nature Genetics, 1.1M sample) PGS explains 11-13% of EA variance: https://t.co/GGUmhV0oDz Okbay et al. 2022 (Nature Genetics, 3M sample) explains 12-16%: https://t.co/FHhIb6Xkhu For GCSE-level achievement, Alleg…

And this: https://t.co/nBd4YFluAr

@ndosenbach @DukartJuergen Lolz, okay, the trend continues The GWASes get bigger and more predictive https://t.co/K6MF1o5bOQ

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