Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Overview of attention for article published in BBA - Proteins & Proteomics, March 2019

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In the top 25% of all research outputs scored by Altmetric
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Azole antifungals target 14-alpha demethylase, an enzyme in fungi that makes ergosterol, a portion of the fungi's cell membrane. Because this enzyme is also a CYP enzyme (CYP51), azole antifungals have many drug-drug interactions. #OTILT https://t.co/W…

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