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Conjugated Quantum Dots Inhibit the Amyloid β (1–42) Fibrillation Process

Overview of attention for article published in International Journal of Alzheimer's Disease, March 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#26 of 249)
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

patent
6 patents
f1000
1 research highlight platform

Readers on

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44 Mendeley
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Article details
Title
Conjugated Quantum Dots Inhibit the Amyloid β (1–42) Fibrillation Process
Published in
International Journal of Alzheimer's Disease, March 2011
DOI 10.4061/2011/502386
Pubmed ID
Authors
Abstract

Nanoparticles have enormous potential in diagnostic and therapeutic studies. We have demonstrated that the amyloid beta mixed with and conjugated to dihydrolipoic acid- (DHLA) capped CdSe/ZnS quantum dots (QDs) of size approximately 2.5 nm can be used to reduce the fibrillation process. Transmission electron microscopy (TEM) and atomic force microscopy (AFM) were used as tools for analysis of fibrillation. There is a significant change in morphology of fibrils when amyloid β (1-42) (Aβ (1-42)) is mixed or conjugated to the QDs. The length and the width of the fibrils vary under modified conditions. Thioflavin T (ThT) fluorescence supports the decrease in fibril formation in presence of DHLA-capped QDs.

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Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
India 2 5%
Iran, Islamic Republic of 1 2%
Spain 1 2%
Chile 1 2%
Unknown 39 89%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Ph. D. Student 13 30%
Student > Doctoral Student 6 14%
Student > Master 4 9%
Researcher 4 9%
Student > Bachelor 2 5%
Other 3 7%
Unknown 12 27%
Readers by discipline
Readers by discipline Count As %
Agricultural and Biological Sciences 8 18%
Chemistry 5 11%
Physics and Astronomy 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Biochemistry, Genetics and Molecular Biology 3 7%
Other 8 18%
Unknown 13 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2025.
All research outputs
#2,878,898
of 34,559,526 outputs
Outputs from International Journal of Alzheimer's Disease
#26
of 249 outputs
Outputs of similar age
#11,850
of 162,372 outputs
Outputs of similar age from International Journal of Alzheimer's Disease
#4
of 18 outputs
Altmetric has tracked 34,559,526 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 249 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 162,372 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.