Increased Levels of the Parkinson’s Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status

RT @interactivefly: Di Leva, F., Filosi, M., ..., Hicks, A. A. and Corti, C. (2023). Increased Levels of the Parkinson's Disease-Associat…

Di Leva, F., Filosi, M., ..., Hicks, A. A. and Corti, C. (2023). Increased Levels of the Parkinson's Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of alpha-Synuclein, Independent of Mutation Status. Int J Mol Sci 24(3). htt…

PD関連遺伝子ITPKBの発現量増加は変異の有無によらず、α-シヌクレインの発現量増加と相関する 「GWASで同定されたリスク遺伝子Inositol-trisphosphate 3-kinase B（ITPKB）のオルソログであるIP3K2が生体内のα-シヌクレインの毒性を調節する能力検証」 Molecular Sciences …