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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders
|
|---|---|
| Published in |
Cellular and Molecular Neurobiology, February 2023
|
| DOI | 10.1007/s10571-023-01324-w |
| Pubmed ID | |
| Authors |
Sheikh Bilal Ahmad, Aarif Ali, Midhat Bilal, Shahzada Mudasir Rashid, Amir Bashir Wani, Rahil Razak Bhat, Muneeb U. Rehman |
| Abstract |
Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many living organisms. In human beings, pineal gland is the major site for melatonin production and to lesser extent by retina, lymphocytes, bone marrow, gastrointestinal tract, and thymus. Melatonin as a neurohormone is released into circulation wherein it penetrates all tissues of the body. Melatonin synthesis and secretion is supressed by light and enhanced by dark. Melatonin mostly exerts its effect through different pathways with melatonin receptor 1 (MT1) and melatonin receptor 2 (MT2) being the predominant type of receptor that are mainly expressed by many mammalian organs. Melatonin helps to regulate sleep patterns and circadian rhythms. In addition, melatonin acts as an antioxidant and scavenges excessive free radicals generated in the body by anti-excitatory and anti-inflammatory properties. A multiple array of other functions are displayed by melatonin that include oncostatic, hypnotic, immune regulation, reproduction, puberty timing, mood disorders, and transplantation. Deficiencies in the production or synthesis of melatonin have been found to be associated with onset of many disorders like breast cancer and neurodegenerative disorders. Melatonin could be used as potential analgesic drug in diseases associated with pain and it has quite promising role there. In the past century, a growing interest has been developed regarding the wide use of melatonin in treating various diseases like inflammatory, gastrointestinal, cancer, mood disorders, and others. Several melatonin agonists have been synthesized and are widely used in disease treatment. In this review, an effort has been made to describe the biochemistry of melatonin along with its therapeutic potential in various diseases of humans. |
X Demographics
The data shown below were collected from the profiles of 39 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 10% |
| Colombia | 2 | 5% |
| Poland | 2 | 5% |
| Uruguay | 2 | 5% |
| Australia | 1 | 3% |
| Pakistan | 1 | 3% |
| India | 1 | 3% |
| Spain | 1 | 3% |
| Austria | 1 | 3% |
| Other | 3 | 8% |
| Unknown | 21 | 54% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 29 | 74% |
| Scientists | 5 | 13% |
| Practitioners (doctors, other healthcare professionals) | 4 | 10% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 99 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 8% |
| Student > Bachelor | 6 | 6% |
| Unspecified | 5 | 5% |
| Researcher | 5 | 5% |
| Professor | 4 | 4% |
| Other | 19 | 19% |
| Unknown | 52 | 53% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 9 | 9% |
| Medicine and Dentistry | 9 | 9% |
| Agricultural and Biological Sciences | 8 | 8% |
| Unspecified | 5 | 5% |
| Nursing and Health Professions | 4 | 4% |
| Other | 11 | 11% |
| Unknown | 53 | 54% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2024.
All research outputs
#2,044,326
of 25,530,891 outputs
Outputs from Cellular and Molecular Neurobiology
#40
of 1,100 outputs
Outputs of similar age
#42,909
of 475,728 outputs
Outputs of similar age from Cellular and Molecular Neurobiology
#2
of 18 outputs
Altmetric has tracked 25,530,891 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,100 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 475,728 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.