Title |
IgG4 related disease and aortitis: an up-to-date review
|
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Published in |
Scandinavian Journal of Rheumatology. Supplement, February 2023
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DOI | 10.1080/03009742.2022.2145744 |
Pubmed ID | |
Authors |
N Jayachamarajapura Onkaramurthy, SC Suresh, P Theetha Kariyanna, A Jayarangaiah, G Prakash, B Raju |
Abstract |
Aortic involvement in immunoglobulin G4-related disease (IgG4-RD) is extremely rare and is often overlooked during the aortitis work-up. IgG4-related aortitis differs from non-IgG4-related aortitis in its histopathological features, site of involvement, laboratory markers, and treatment options. The histopathological examination of the vessel walls characteristically reveals adventitial thickening with intimal sparing, typically affecting the infrarenal abdominal aorta. In addition, inadequate knowledge about the disease often leads to delayed or missed diagnosis and undermanagement of a potentially treatable condition. Hence, in this paper, we review the unique clinical manifestations, laboratory markers, diagnostic features, current treatment strategies, and novel experimental therapeutic options in the management of IgG4-related aortitis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 17% |
Colombia | 2 | 17% |
Ecuador | 1 | 8% |
Spain | 1 | 8% |
Unknown | 6 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 8 | 67% |
Scientists | 2 | 17% |
Practitioners (doctors, other healthcare professionals) | 2 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 1 | 33% |
Student > Doctoral Student | 1 | 33% |
Student > Master | 1 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 3 | 100% |