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Postoperative delirium, neuroinflammation, and influencing factors of postoperative delirium: A review

Overview of attention for article published in Medicine (Wolters Kluwer), February 2023
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

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95 X users

Citations

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12 Dimensions

Readers on

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18 Mendeley
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Title
Postoperative delirium, neuroinflammation, and influencing factors of postoperative delirium: A review
Published in
Medicine (Wolters Kluwer), February 2023
DOI 10.1097/md.0000000000032991
Pubmed ID
Authors

M. Z. Xiao, C. X. Liu, L. G. Zhou, Y. Yang, Y. Wang

Abstract

Postoperative delirium (POD) is an acute cognitive dysfunction that is mainly characterized by memory impairment and disturbances in consciousness. POD can prolong the hospital stay and increase the 1-month mortality rate of patients. The overall incidence of POD is approximately 23%, and its prevalence can go up to 50% in high-risk surgeries. Neuroinflammation is an important pathogenic mechanism of POD that mediates microglial activation and leads to synaptic remodeling. Neuroinflammation, as an indispensable pathogenesis of POD, can occur due to a variety of factors, including aseptic inflammation caused by surgery, effects of anesthetic drugs, disruption of the blood-brain barrier, and epigenetics. Understanding these factors and avoiding the occurrence of risk factors may help prevent POD in time. This review provides a brief overview of POD and neuroinflammation and summarizes various factors affecting POD development mediated by neuroinflammation, which may serve as future targets for the prevention and treatment of POD.

X Demographics

X Demographics

The data shown below were collected from the profiles of 95 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 22%
Lecturer 1 6%
Student > Doctoral Student 1 6%
Student > Ph. D. Student 1 6%
Researcher 1 6%
Other 2 11%
Unknown 8 44%
Readers by discipline Count As %
Medicine and Dentistry 8 44%
Nursing and Health Professions 1 6%
Materials Science 1 6%
Social Sciences 1 6%
Unknown 7 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 51. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2023.
All research outputs
#839,995
of 25,617,409 outputs
Outputs from Medicine (Wolters Kluwer)
#189
of 16,414 outputs
Outputs of similar age
#18,412
of 427,312 outputs
Outputs of similar age from Medicine (Wolters Kluwer)
#5
of 326 outputs
Altmetric has tracked 25,617,409 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 16,414 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 427,312 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 326 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.