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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
|
|---|---|
| Published in |
Nature Immunology, March 2023
|
| DOI | 10.1038/s41590-023-01445-w |
| Pubmed ID | |
| Authors |
Jonathan Muri, Valentina Cecchinato, Andrea Cavalli, Akanksha A. Shanbhag, Milos Matkovic, Maira Biggiogero, Pier Andrea Maida, Jacques Moritz, Chiara Toscano, Elaheh Ghovehoud, Raffaello Furlan, Franca Barbic, Antonio Voza, Guendalina De Nadai, Carlo Cervia, Yves Zurbuchen, Patrick Taeschler, Lilly A. Murray, Gabriela Danelon-Sargenti, Simone Moro, Tao Gong, Pietro Piffaretti, Filippo Bianchini, Virginia Crivelli, Lucie Podešvová, Mattia Pedotti, David Jarrossay, Jacopo Sgrignani, Sylvia Thelen, Mario Uhr, Enos Bernasconi, Andri Rauch, Antonio Manzo, Adrian Ciurea, Marco B. L. Rocchi, Luca Varani, Bernhard Moser, Barbara Bottazzi, Marcus Thelen, Brian A. Fallon, Onur Boyman, Alberto Mantovani, Christian Garzoni, Alessandra Franzetti-Pellanda, Mariagrazia Uguccioni, Davide F. Robbiani |
| Abstract |
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are associated with adverse coronavirus disease 2019 (COVID-19) outcomes. Here we discovered that antibodies against specific chemokines were omnipresent post-COVID-19, were associated with favorable disease outcome and negatively correlated with the development of long COVID at 1 yr post-infection. Chemokine antibodies were also present in HIV-1 infection and autoimmune disorders, but they targeted different chemokines compared with COVID-19. Monoclonal antibodies derived from COVID-19 convalescents that bound to the chemokine N-loop impaired cell migration. Given the role of chemokines in orchestrating immune cell trafficking, naturally arising chemokine antibodies may modulate the inflammatory response and thus bear therapeutic potential. |
X Demographics
The data shown below were collected from the profiles of 346 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 56 | 16% |
| United Kingdom | 19 | 5% |
| Germany | 10 | 3% |
| Canada | 7 | 2% |
| France | 6 | 2% |
| Netherlands | 5 | 1% |
| Sweden | 4 | 1% |
| Mexico | 4 | 1% |
| Austria | 4 | 1% |
| Other | 36 | 10% |
| Unknown | 195 | 56% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 280 | 81% |
| Scientists | 39 | 11% |
| Practitioners (doctors, other healthcare professionals) | 18 | 5% |
| Science communicators (journalists, bloggers, editors) | 9 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 75 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 15% |
| Student > Ph. D. Student | 8 | 11% |
| Student > Doctoral Student | 8 | 11% |
| Student > Master | 6 | 8% |
| Student > Bachelor | 4 | 5% |
| Other | 12 | 16% |
| Unknown | 26 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 15 | 20% |
| Biochemistry, Genetics and Molecular Biology | 9 | 12% |
| Medicine and Dentistry | 8 | 11% |
| Unspecified | 4 | 5% |
| Agricultural and Biological Sciences | 3 | 4% |
| Other | 8 | 11% |
| Unknown | 28 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 247. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2024.
All research outputs
#153,869
of 25,775,807 outputs
Outputs from Nature Immunology
#88
of 4,236 outputs
Outputs of similar age
#4,076
of 427,178 outputs
Outputs of similar age from Nature Immunology
#4
of 75 outputs
Altmetric has tracked 25,775,807 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,236 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 36.0. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 427,178 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.