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Alterations in Epidermal Biophysical Properties in Autistic Children

Overview of attention for article published in Skin Pharmacology and Physiology, March 2023
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Title
Alterations in Epidermal Biophysical Properties in Autistic Children
Published in
Skin Pharmacology and Physiology, March 2023
DOI 10.1159/000530140
Pubmed ID
Authors

Bin Wang, You-Dong Li, Zi-Yan Wang, Jia-Qing Zhao, Guo-Qiang Zhang, Mao-Qiang Man

Abstract

Autism is a neurodevelopmental disorder. Individuals with autism can exhibit multiple neurological symptoms such as deficit in social communication, restricted interests and repetitive behaviors. Recent study showed that murine model of autism displays an increased transepidermal water loss (TEWL) and dry skin. But whether epidermal functions are also altered in children with autism is unknown. In the present study, TEWL, stratum corneum hydration and skin surface pH were compared between children with autism (N=56) and normal controls (N=48). Our results showed that children with autism exhibited lower stratum corneum hydration levels, higher TEWL and elevated skin surface pH in comparison to normal controls (p<0.0001 for all). These results demonstrate that children with autism exhibit epidermal dysfunction.

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Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2023.
All research outputs
#16,237,186
of 25,654,806 outputs
Outputs from Skin Pharmacology and Physiology
#466
of 597 outputs
Outputs of similar age
#218,791
of 428,425 outputs
Outputs of similar age from Skin Pharmacology and Physiology
#1
of 5 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 597 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 428,425 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them