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Inclisiran: present and future perspectives of a new effective LDL cholesterol-lowering agent

Overview of attention for article published in Current Opinion in Lipidology, March 2023
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

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6 Mendeley
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Title
Inclisiran: present and future perspectives of a new effective LDL cholesterol-lowering agent
Published in
Current Opinion in Lipidology, March 2023
DOI 10.1097/mol.0000000000000877
Pubmed ID
Authors

Salvatore Giordano, Alberto Polimeni, Giovanni Esposito, Ciro Indolfi, Carmen Spaccarotella

Abstract

To highlight critical aspects of inclisiran, from preclinical studies to current recommendations in clinical practice and future perspectives. Inclisiran use has been recently approved by regulatory agencies. The evidence of its efficacy and safety makes it a promising therapeutical tool for treating dyslipidemias. The link between LDL-cholesterol and atherosclerotic cardiovascular disease (ASCVD) is well established. Inclisiran, a small interfering RNA, has proven its safety and efficacy in reducing LDL-cholesterol, and FDA and EMA have recently approved its use. This review illustrates the development, structure, and mechanism of action of inclisiran and provides information regarding its efficacy, safety, and current recommendation in clinical practice. Moreover, it provides key information on the most recent/ongoing trials that will help us to implement the use of inclisiran in clinical practice.

X Demographics

X Demographics

The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 2 33%
Unspecified 1 17%
Other 1 17%
Researcher 1 17%
Unknown 1 17%
Readers by discipline Count As %
Unspecified 1 17%
Pharmacology, Toxicology and Pharmaceutical Science 1 17%
Medicine and Dentistry 1 17%
Unknown 3 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2023.
All research outputs
#2,601,223
of 25,081,505 outputs
Outputs from Current Opinion in Lipidology
#85
of 1,169 outputs
Outputs of similar age
#50,633
of 413,726 outputs
Outputs of similar age from Current Opinion in Lipidology
#2
of 12 outputs
Altmetric has tracked 25,081,505 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,169 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 413,726 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.