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The innate immune response in tauopathies

Overview of attention for article published in European Journal of Immunology, May 2023
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
twitter
39 X users
peer_reviews
1 peer review site

Citations

dimensions_citation
2 Dimensions

Readers on

mendeley
15 Mendeley
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Title
The innate immune response in tauopathies
Published in
European Journal of Immunology, May 2023
DOI 10.1002/eji.202250266
Pubmed ID
Authors

Alexis M. Johnson, John R. Lukens

Abstract

Tauopathies, which include frontotemporal dementia, Alzheimer's disease, and chronic traumatic encephalopathy, are a class of neurological disorders resulting from pathogenic tau aggregates. These aggregates disrupt neuronal health and function leading to the cognitive and physical decline of tauopathy patients. Genome-wide association studies and clinical evidence have brought to light the large role of the immune system in inducing and driving tau-mediated pathology. More specifically, innate immune genes are found to harbor tauopathy risk alleles and innate immune pathways are upregulated throughout the course of disease. Experimental evidence has expanded on these findings by describing pivotal roles for the innate immune system in the regulation of tau kinases and tau aggregates. In this review, we summarize the literature implicating innate immune pathways as drivers of tauopathy. This article is protected by copyright. All rights reserved.

X Demographics

X Demographics

The data shown below were collected from the profiles of 39 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Unspecified 2 13%
Student > Ph. D. Student 2 13%
Student > Bachelor 1 7%
Professor 1 7%
Other 2 13%
Unknown 4 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 20%
Neuroscience 3 20%
Unspecified 2 13%
Business, Management and Accounting 1 7%
Social Sciences 1 7%
Other 1 7%
Unknown 4 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2023.
All research outputs
#1,311,410
of 25,517,918 outputs
Outputs from European Journal of Immunology
#58
of 6,936 outputs
Outputs of similar age
#27,019
of 407,555 outputs
Outputs of similar age from European Journal of Immunology
#5
of 54 outputs
Altmetric has tracked 25,517,918 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,936 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 407,555 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.