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Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma

Overview of attention for article published in Clinical and Molecular Hepatology, March 2023
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#3 of 231)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

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41 news outlets
blogs
2 blogs
twitter
2 X users

Citations

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193 Dimensions

Readers on

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220 Mendeley
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Title
Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma
Published in
Clinical and Molecular Hepatology, March 2023
DOI 10.3350/cmh.2023.0089
Pubmed ID
Authors

Yee Hui Yeo, Jamil S. Samaan, Wee Han Ng, Peng-Sheng Ting, Hirsh Trivedi, Aarshi Vipani, Walid Ayoub, Ju Dong Yang, Omer Liran, Brennan Spiegel, Alexander Kuo

Abstract

Patients with cirrhosis and hepatocellular carcinoma (HCC) require extensive and personalized care to improve outcomes. ChatGPT (Generative Pre-trained Transformer), a large language model, holds the potential to provide professional yet patient-friendly support. We aimed to examine the accuracy and reproducibility of ChatGPT in answering questions regarding knowledge, management, and emotional support for cirrhosis and HCC. ChatGPT's responses to 164 questions were independently graded by two transplant hepatologists and resolved by a third reviewer. The performance of ChatGPT was also assessed using two published questionnaires and 26 questions formulated from the quality measures of cirrhosis management. Finally, its emotional support capacity was tested. We showed that ChatGPT regurgitated extensive knowledge of cirrhosis (79.1% correct) and HCC (74.0% correct), but only small proportions (47.3% in cirrhosis, 41.1% in HCC) were labeled as comprehensive. The performance was better in basic knowledge, lifestyle, and treatment than in the domains of diagnosis and preventive medicine. For the quality measures, the model answered 76.9% of questions correctly but failed to specify decision-making cut-offs and treatment durations. ChatGPT lacked knowledge of regional guidelines variations, such as HCC screening criteria. However, it provided practical and multifaceted advice to patients and caregivers regarding the next steps and adjusting to a new diagnosis. We analyzed the areas of robustness and limitations of ChatGPT's responses on the management of cirrhosis and HCC and relevant emotional support. ChatGPT may have a role as an adjunct informational tool for patients and physicians to improve outcomes.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 220 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 220 100%

Demographic breakdown

Readers by professional status Count As %
Other 13 6%
Lecturer 13 6%
Researcher 9 4%
Student > Ph. D. Student 8 4%
Student > Doctoral Student 8 4%
Other 36 16%
Unknown 133 60%
Readers by discipline Count As %
Medicine and Dentistry 35 16%
Social Sciences 10 5%
Computer Science 8 4%
Unspecified 8 4%
Business, Management and Accounting 6 3%
Other 22 10%
Unknown 131 60%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 297. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2023.
All research outputs
#111,723
of 24,679,965 outputs
Outputs from Clinical and Molecular Hepatology
#3
of 231 outputs
Outputs of similar age
#2,905
of 407,153 outputs
Outputs of similar age from Clinical and Molecular Hepatology
#3
of 16 outputs
Altmetric has tracked 24,679,965 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 231 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 407,153 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.