Title |
SARS-CoV-2 Omicron variant shedding during respiratory activities
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Published in |
International Journal of Infectious Diseases, March 2023
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DOI | 10.1016/j.ijid.2023.03.029 |
Pubmed ID | |
Authors |
Kai Sen Tan, Sean Wei Xiang Ong, Ming Hui Koh, Douglas Jie Wen Tay, Daryl Zheng Hao Aw, Yi Wei Nah, Mohammed Ridzwan Bin Abdullah, Kristen K Coleman, Donald K Milton, Justin Jang Hann Chu, Vincent T K Chow, Paul Anantharajah Tambyah, Kwok Wai Tham |
Abstract |
As the world transitions to COVID-19 endemicity, studies focusing on aerosol shedding of highly transmissible SARS-CoV-2 variants of concern (VOCs) are vital for the calibration of infection control measures against VOCs that are likely to circulate seasonally. This follow-up G-II aerosol sampling study aims to compare the aerosol shedding patterns of Omicron VOC samples with pre-Omicron variants analyzed in our previous study. Coarse and fine aerosol samples from 47 SARS-CoV-2 infected patients were collected during various respiratory activities (passive breathing, talking, and singing) and analyzed via reverse transcription quantitative polymerase chain reaction (RT-qPCR) and virus culture. Compared to patients infected with pre-Omicron variants, comparable SARS-CoV-2 RNA copy numbers were detectable in aerosol samples of Omicron infected patients despite being fully vaccinated. Omicron-infected patients also showed a slight increase in viral aerosol shedding during breathing activities, and were more likely to have persistent aerosol shedding beyond 7 days post-disease onset. This follow-up study reaffirms the aerosol shedding properties of Omicron, and should guide continued layering of public health interventions even in highly vaccinated populations. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 236 | 15% |
United States | 68 | 4% |
United Kingdom | 55 | 4% |
Canada | 53 | 3% |
Australia | 20 | 1% |
Germany | 18 | 1% |
Austria | 10 | <1% |
Switzerland | 8 | <1% |
France | 8 | <1% |
Other | 89 | 6% |
Unknown | 960 | 63% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1411 | 93% |
Scientists | 62 | 4% |
Practitioners (doctors, other healthcare professionals) | 38 | 2% |
Science communicators (journalists, bloggers, editors) | 13 | <1% |
Unknown | 1 | <1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 50% |
Student > Ph. D. Student | 2 | 13% |
Professor | 1 | 6% |
Unspecified | 1 | 6% |
Other | 1 | 6% |
Other | 1 | 6% |
Unknown | 2 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 3 | 19% |
Engineering | 2 | 13% |
Immunology and Microbiology | 2 | 13% |
Unspecified | 1 | 6% |
Environmental Science | 1 | 6% |
Other | 2 | 13% |
Unknown | 5 | 31% |