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Non-Pharmacological Treatments in Lewy Body Disease: A Systematic Review

Overview of attention for article published in Dementia and Geriatric Cognitive Disorders, March 2023
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

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1 news outlet
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Citations

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4 Dimensions

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28 Mendeley
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Title
Non-Pharmacological Treatments in Lewy Body Disease: A Systematic Review
Published in
Dementia and Geriatric Cognitive Disorders, March 2023
DOI 10.1159/000529256
Pubmed ID
Authors

Lucia Guidi, Stefania Evangelisti, Andrea Siniscalco, Raffaele Lodi, Caterina Tonon, Micaela Mitolo

Abstract

Lewy body disease (LBD) is the second most common neurodegenerative disorder in patients older than 65 years. LBD is characterized by heterogeneous symptoms like fluctuation in attention, visual hallucinations, Parkinsonism, and REM sleep behaviour disorders. Considering the relevant social impact of the disease, identifying effective non-pharmacological treatments is becoming a priority. The aim of this systematic review was to provide an up-to-date literature review of the most effective non-pharmacological treatments in patients with LBD, focussing on evidence-based interventions. Following PRISMA criteria, we carried out a systematic search through three databases (PubMed, Cochrane Libraries, and PEDro) including physical therapy (PT), cognitive rehabilitation (CR), light therapy (LT), transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS), electroconvulsive therapy (ECT), deep brain stimulation (DBS). All studies were qualitatively assessed using standardized tools (CARE and EPHPP). We obtained a total of 1,220 studies of which 23 original articles met eligibility criteria for inclusion. The total number of LBD patients included was 231; mean age was 69.98, predominantly men (68%). Some PT studies highlighted improvements in motor deficits. CR produced significant improvements in mood, cognition, and patient's quality of life and satisfaction. LT outlined a partial trend of improvements in mood and sleep quality. DBS, ECT, and TMS showed some partial improvements mainly on neuropsychiatric symptoms, whereas tDCS provided partial improvements in attention. This review highlights the efficacy of some evidence-based rehabilitation studies in LBD; however, further randomized controlled trials with larger samples are needed to provide definitive recommendations.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 11%
Student > Bachelor 3 11%
Researcher 2 7%
Student > Master 2 7%
Unspecified 1 4%
Other 1 4%
Unknown 16 57%
Readers by discipline Count As %
Social Sciences 2 7%
Nursing and Health Professions 2 7%
Neuroscience 2 7%
Business, Management and Accounting 1 4%
Agricultural and Biological Sciences 1 4%
Other 4 14%
Unknown 16 57%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2024.
All research outputs
#2,954,482
of 25,269,846 outputs
Outputs from Dementia and Geriatric Cognitive Disorders
#109
of 1,048 outputs
Outputs of similar age
#55,347
of 411,993 outputs
Outputs of similar age from Dementia and Geriatric Cognitive Disorders
#1
of 12 outputs
Altmetric has tracked 25,269,846 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,048 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 411,993 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.