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Cell‐free RNA for the liquid biopsy of gastrointestinal cancer

Overview of attention for article published in Wiley Interdisciplinary Reviews: RNA, April 2023
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (55th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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3 X users

Citations

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Title
Cell‐free RNA for the liquid biopsy of gastrointestinal cancer
Published in
Wiley Interdisciplinary Reviews: RNA, April 2023
DOI 10.1002/wrna.1791
Pubmed ID
Authors

Shaozhen Xing, Yumin Zhu, Yaxian You, Siqi Wang, Hongke Wang, Meng Ning, Heyue Jin, Zhengxia Liu, Xinhua Zhang, Chunzhao Yu, Zhi John Lu

Abstract

Gastrointestinal (GI) cancer includes many cancer types, such as esophageal, liver, gastric, pancreatic, and colorectal cancer. As the cornerstone of personalized medicine for GI cancer, liquid biopsy based on noninvasive biomarkers provides promising opportunities for early diagnosis and dynamic treatment management. Recently, a growing number of studies have demonstrated the potential of cell-free RNA (cfRNA) as a new type of noninvasive biomarker in body fluids, such as blood, saliva, and urine. Meanwhile, transcriptomes based on high-throughput RNA detection technologies keep discovering new cfRNA biomarkers. In this review, we introduce the origins and applications of cfRNA, describe its detection and qualification methods in liquid biopsy, and summarize a comprehensive list of cfRNA biomarkers in different GI cancer types. Moreover, we also discuss perspective studies of cfRNA to overcome its current limitations in clinical applications. This article is categorized under: RNA in Disease and Development > RNA in Disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 31%
Professor 2 15%
Researcher 1 8%
Student > Doctoral Student 1 8%
Unknown 5 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 23%
Nursing and Health Professions 1 8%
Business, Management and Accounting 1 8%
Unknown 8 62%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2023.
All research outputs
#15,237,808
of 25,872,466 outputs
Outputs from Wiley Interdisciplinary Reviews: RNA
#367
of 688 outputs
Outputs of similar age
#182,698
of 416,793 outputs
Outputs of similar age from Wiley Interdisciplinary Reviews: RNA
#4
of 10 outputs
Altmetric has tracked 25,872,466 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 688 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 416,793 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.