Title |
Association of Gestational Diabetes Mellitus and Perinatal Maternal Depression with Early Childhood Behavioral Problems: An Environmental Influences on Child Health Outcomes (ECHO) Study
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Published in |
Child Development, May 2023
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DOI | 10.1111/cdev.13938 |
Pubmed ID | |
Authors |
Lauren C. Shuffrey, Santiago Morales, Melanie H. Jacobson, Michelle Bosquet Enlow, Akhgar Ghassabian, Amy E. Margolis, Maristella Lucchini, Kecia N. Carroll, Rosa M. Crum, Dana Dabelea, Arielle Deutsch, William P. Fifer, Brandon Goldson, Christine W. Hockett, W. Alex Mason, Lisette T. Jacobson, Thomas G. O'Connor, Nicolò Pini, Yael Rayport, Ayesha Sania, Leonardo Trasande, Rosalind J. Wright, Seonjoo Lee, Catherine Monk, program collaborators for Environmental influences on Child Health Outcomes |
Abstract |
This study examined the association of gestational diabetes mellitus (GDM), prenatal, and postnatal maternal depressive symptoms with externalizing, internalizing, and autism spectrum problems on the Preschool Child Behavior Checklist in 2379 children aged 4.12 ± 0.60 (48% female; 47% White, 32% Black, 15% Mixed Race, 4% Asian, <2% American Indian/Alaskan Native, <2% Native Hawaiian; 23% Hispanic). Data were collected from the NIH Environmental influences on Child Health Outcomes (ECHO) Program from 2009-2021. GDM, prenatal, and postnatal maternal depressive symptoms were each associated with increased child externalizing and internalizing problems. GDM was associated with increased autism behaviors only among children exposed to perinatal maternal depressive symptoms above the median level. Stratified analyses revealed a relation between GDM and child outcomes in males only. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 5 | 45% |
Unknown | 6 | 55% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 55% |
Scientists | 4 | 36% |
Practitioners (doctors, other healthcare professionals) | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 2 | 15% |
Student > Ph. D. Student | 1 | 8% |
Professor > Associate Professor | 1 | 8% |
Student > Master | 1 | 8% |
Unknown | 8 | 62% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 2 | 15% |
Social Sciences | 1 | 8% |
Neuroscience | 1 | 8% |
Medicine and Dentistry | 1 | 8% |
Unknown | 8 | 62% |