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Immortalized Bovine Satellite Cells for Cultured Meat Applications

Overview of attention for article published in ACS Synthetic Biology, May 2023
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 2,904)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
39 news outlets
blogs
1 blog
twitter
41 X users
video
1 YouTube creator

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
65 Mendeley
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Title
Immortalized Bovine Satellite Cells for Cultured Meat Applications
Published in
ACS Synthetic Biology, May 2023
DOI 10.1021/acssynbio.3c00216
Pubmed ID
Authors

Andrew J. Stout, Miles J. Arnett, Kristin Chai, Tina Guo, Lishu Liao, Addison B. Mirliani, Miriam L. Rittenberg, Michelle Shub, Eugene C. White, John S. K. Yuen, Xiaoli Zhang, David L. Kaplan

Abstract

For cultured meat to succeed at scale, muscle cells from food-relevant species must be expanded in vitro in a rapid and reliable manner to produce millions of metric tons of biomass annually. Toward this goal, genetically immortalized cells offer substantial benefits over primary cells, including rapid growth, escape from cellular senescence, and consistent starting cell populations for production. Here, we develop genetically immortalized bovine satellite cells (iBSCs) via constitutive expression of bovine Telomerase reverse transcriptase (TERT) and Cyclin-dependent kinase 4 (CDK4). These cells achieve over 120 doublings at the time of publication and maintain their capacity for myogenic differentiation. They therefore offer a valuable tool to the field, enabling further research and development to advance cultured meat.

X Demographics

X Demographics

The data shown below were collected from the profiles of 41 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 18%
Student > Bachelor 8 12%
Student > Ph. D. Student 7 11%
Student > Doctoral Student 3 5%
Student > Master 3 5%
Other 3 5%
Unknown 29 45%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 16 25%
Agricultural and Biological Sciences 9 14%
Medicine and Dentistry 2 3%
Engineering 2 3%
Unspecified 1 2%
Other 4 6%
Unknown 31 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 327. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2023.
All research outputs
#101,940
of 25,394,764 outputs
Outputs from ACS Synthetic Biology
#1
of 2,904 outputs
Outputs of similar age
#2,581
of 403,988 outputs
Outputs of similar age from ACS Synthetic Biology
#1
of 83 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,904 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 403,988 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.