| Title |
Vitamin D: beyond bone
|
|---|---|
| Published in |
Annals of the New York Academy of Sciences, May 2013
|
| DOI | 10.1111/nyas.12129 |
| Pubmed ID | |
| Authors | |
| Abstract |
In recent years, vitamin D has been received increased attention due to the resurgence of vitamin D deficiency and rickets in developed countries and the identification of extraskeletal effects of vitamin D, suggesting unexpected benefits of vitamin D in health and disease, beyond bone health. The possibility of extraskeletal effects of vitamin D was first noted with the discovery of the vitamin D receptor (VDR) in tissues and cells that are not involved in maintaining mineral homeostasis and bone health, including skin, placenta, pancreas, breast, prostate and colon cancer cells, and activated T cells. However, the biological significance of the expression of the VDR in different tissues is not fully understood, and the role of vitamin D in extraskeletal health has been a matter of debate. This report summarizes recent research on the roles for vitamin D in cancer, immunity and autoimmune diseases, cardiovascular and respiratory health, pregnancy, obesity, erythropoiesis, diabetes, muscle function, and aging. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 17% |
| Switzerland | 2 | 17% |
| Canada | 1 | 8% |
| France | 1 | 8% |
| Mexico | 1 | 8% |
| Australia | 1 | 8% |
| Unknown | 4 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 92% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | <1% |
| Spain | 3 | <1% |
| Uruguay | 1 | <1% |
| United States | 1 | <1% |
| Russia | 1 | <1% |
| Qatar | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 510 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 88 | 17% |
| Student > Bachelor | 70 | 13% |
| Student > Ph. D. Student | 60 | 12% |
| Researcher | 56 | 11% |
| Student > Postgraduate | 31 | 6% |
| Other | 104 | 20% |
| Unknown | 112 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 192 | 37% |
| Agricultural and Biological Sciences | 67 | 13% |
| Nursing and Health Professions | 33 | 6% |
| Biochemistry, Genetics and Molecular Biology | 32 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 2% |
| Other | 57 | 11% |
| Unknown | 129 | 25% |