Continuous treatment with the D2 dopamine receptor agonist quinpirole decreases D2 dopamine receptors, D2 dopamine receptor messenger RNA and proenkephalin messenger RNA, and increases mu opioid…

In this context no, although desensitizing some receptors...

User Cbd_7ohm, in the Neuroscience: Your brain on reddit subreddit, 05 Apr 2021

In this context no, although desensitizing some receptors with at least some agonists actually increases receptor production…