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A combination of N-acetyl cysteine and propolis attenuates oxidative-inflammatory parameters during COPD exacerbation.

Overview of attention for article published in European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] NLMUID: 9717360, April 2022
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (75th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

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1 news outlet

Citations

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3 Dimensions

Readers on

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16 Mendeley
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Title
A combination of N-acetyl cysteine and propolis attenuates oxidative-inflammatory parameters during COPD exacerbation.
Published in
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] NLMUID: 9717360, April 2022
DOI 10.26355/eurrev_202204_28481
Pubmed ID
Authors

O Žuža, R Minić, J Kotur-Stevuljević, D Žujović, B Đorđević, A Ilić

Abstract

The aim of this study was to determine any differences in oxidative stress and inflammation parameters in COPD patients treated with either N-acetyl cysteine (NAC) alone or with NAC in combination with propolis (NACP). Forty COPD patients in the exacerbation phase were enrolled into the study and were treated with either NAC (NAC group; n=20) or NACP (NACP group; n=20) twice daily for one month. Redox status was determined by measuring superoxide anion (O2.-), advanced oxidation protein products (AOPP), total oxidative status (TOS), prooxidative-antioxidant balance (PAB), malondialdehyde (MDA), ischemia modified albumin (IMA) and several other antioxidant markers: superoxide dismutase (SOD), paraoxonase 1 (PON1), total sulfhydryl groups (SHG) and total antioxidant status (TAS). Interleukins 6, 8 and 17 were measured as markers of inflammatory status. Both groups had similar socio-demographic and clinical characteristics. After treatment significantly higher SHG [0.446 (0.395-0.516) vs. 0.292 (0.270-0.325), p<0.001] and significantly lower TOS - 50.6 [49.7-53.4 vs. 73.2 (50.9-84.6), p<0.05] - and IMA [0.650 (0.629-0.682) vs. 0.709 (0.667-0.756), p<0.05] - were found in the NACP group compared to the NAC group. Factorial analysis indicated a larger oxidative stress-inflammatory load in the NAC group after treatment. From an oxidative stress and inflammatory status perspective, treatment with NACP was more successful than with NAC. The inclusion of propolis into therapy for COPD patients, especially those in the exacerbation phase, could prove beneficial.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 7 44%
Student > Bachelor 1 6%
Researcher 1 6%
Student > Doctoral Student 1 6%
Student > Master 1 6%
Other 0 0%
Unknown 5 31%
Readers by discipline Count As %
Unspecified 7 44%
Medicine and Dentistry 3 19%
Biochemistry, Genetics and Molecular Biology 1 6%
Unknown 5 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2023.
All research outputs
#4,840,893
of 25,392,582 outputs
Outputs from European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] NLMUID: 9717360
#247
of 3,195 outputs
Outputs of similar age
#105,773
of 447,757 outputs
Outputs of similar age from European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] NLMUID: 9717360
#10
of 97 outputs
Altmetric has tracked 25,392,582 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,195 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,757 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.