Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury

Now, more recent study about this topic; IFN drives neuroinflammation and contributes to neuronal damage, such as loss of synapses, cell death, or white matter injury. https://t.co/cSimP4SFTl

Newell lab @UIowaPeds paper @BioMedCentral: blocking robust type I interferon signaling induced by traumatic brain injury ⬇️ neuroimmune activation driven by microglia&accumulating leukocytes. Associated w neuronal protection in preclinical #TBI model…