An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status

An active #HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status Includes DARE researcher – Prof Nicolas Chomont In @cellhostmicrobe https://t.co/R4RPDhDDnX https://t.co/fqa6C…

https://t.co/DU46FlpbHm "Our data suggest that the active reservoir maintains HIV-specific CD8+ T cell magnitude but prevents their differentiation into functional cells."

https://t.co/DU46FlpbHm "- Residual HIV reservoir levels associated with maintenance of short-lived CD8+ T cells - Low HIV reservoir associated with generation of functional HIV-specific CD8+ T cells"

https://t.co/DU46FlpbHm "- Magnitude of CD8+ T cell response associated with active HIV reservoir size on therapy - Sustained CD8+ T cell responses correlated with a greater HIV provirus decay"