Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

Overview of attention for article published in Nature Genetics, October 2023

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Sources GWAS: www.nature.com/articles/s41... FOURIER: www.ahajournals.org/doi/abs/10.1...

GWAMA Genome-wide association meta-analysis #AbdominalAorticAneurysm 14 cohorts 39k case + 1M ctrl 121 risk loci (97 new!) Lipid & Non-Lipid genes; BOTH LDL-C & non-HDL-C #PCSK9 KO🐭are resistant to elastase-induced #AAA #AortaEd #NatureGenet 2023 www.…

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