Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis

Overview of attention for article published in Nature Communications, November 2023

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James EA, Holers VM, Iyer R, et al. Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis. Nat Commun. 2023;14(1):7637. Published 2023 Nov 22. doi:10.1038/s41467-023-43091-8 https://t.co/Q5fXxpFoD8

https://t.co/nrxbl36qUJ Molecular markers of autoimmunity, such as antibodies to citrullinated protein antigens (ACPA), are detectable prior to inflammatory arthritis (IA) in rheumatoid arthritis (RA) and may define a state that is ‘at-risk’ for future RA…

Dr. V. Michael Holers from @CUAnschutz and colleagues show that multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid #arthritis. 🔗 https://t.co/ZWQpbUApbz https://t.co/62F4HIOW2P

An ACPA (Ab to citrullinated protein antigens) positive at-risk state for arthritis development is associated with multifaceted immune dysregulation https://t.co/qVUQC8ocws

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