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Proteases and Cancer

Overview of attention for book
Proteases and Cancer
Springer US

Table of Contents

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    Book Overview
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    Chapter 1 Web-Based Resources to Investigate Protease Function
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    Chapter 2 N-Terminomics/TAILS of Human Tumor Biopsies and Cancer Cell Lines.
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    Chapter 3 A New Affinity-Based Probe to Profile MMP Active Forms
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    Chapter 4 N-Glycan Insertion for Probing Protein–Protein Interactions and Epitope Mapping
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    Chapter 5 Expression and Purification of Recombinant ADAMTS8
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    Chapter 6 Expression and Purification of Active Monomeric MMP7
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    Chapter 7 Mapping the Binding Sites of MMPs on Types II and III Collagens Using Triple-Helical Peptide Toolkits
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    Chapter 8 Determination of Versikine Levels by Enzyme-Linked Immunosorbent Assay (ELISA)
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    Chapter 9 Methods to Investigate Thrombin Cleavage of Osteopontin (OPN)
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    Chapter 10 Using siRNA Silencing to Analyze ADAM17 in Macrophages
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    Chapter 11 Preparation and Characterization of Collagen–Hyaluronic Acid (Col–HA) Matrices: In Vitro Mimics of the Tumor Microenvironment
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    Chapter 12 Assessment of Invadopodium Formation and Gelatin Degradation in Vitro
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    Chapter 13 Investigation of MT1-MMP Activity in Cancer Cells
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    Chapter 14 Gelatin In Situ Zymography to Study Gelatinase Activity in Colon Cancer Cells Treated with Platelet Microparticles (PMPs)
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    Chapter 15 Interrogating the Impact of Protease Activity on Tumor Progression Using 3D Spheroid Models
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    Chapter 16 Analysis of Matrix Metalloproteinase Activity and Inhibition in Cancer Spheroids
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    Chapter 17 Intravital Microscopy to Study the Effect of Matrix Metalloproteinase Inhibition on Acute Myeloid Leukemia Cell Migration in the Bone Marrow
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    Chapter 18 Fluorescence-Based Peptidolytic Assay for High-Throughput Screening of MMP14 Inhibitors
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    Chapter 19 Generation of Protease Inhibitory Antibodies by Functional In Vivo Selection
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    Chapter 20 Engineering Selective TIMPs Using a Counter-Selective Screening Strategy.
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    Chapter 21 Engineering New Protease Inhibitors Using α 2 -Macroglobulin
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    Chapter 22 Design of Bioengineered Peptides/Proteases as Anti-cancer Reagents with Integrated Omics and Machine Learning Approaches.
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