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Redox and metabolic reprogramming in breast cancer and cancer‐associated adipose tissue

Overview of attention for article published in Febs Letters, December 2023
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Title
Redox and metabolic reprogramming in breast cancer and cancer‐associated adipose tissue
Published in
Febs Letters, December 2023
DOI 10.1002/1873-3468.14794
Pubmed ID
Authors

Tamara Zakic, Vanja Pekovic‐Vaughan, Aleksandra Cvoro, Aleksandra Korac, Aleksandra Jankovic, Bato Korac

Abstract

Redox and metabolic processes are tightly coupled in both physiological and pathological conditions. In cancer, their integration occurs at multiple levels and is characterised by synchronised reprogramming both in the tumour tissue and its specific but heterogeneous microenvironment. In breast cancer, the principal microenvironment is the cancer-associated adipose tissue (CAAT). Understanding how the redox-metabolic reprogramming becomes coordinated in human breast cancer is imperative both for cancer prevention and for the establishment of new therapeutic approaches. This review aims to provide an overview of the current knowledge of the redox profiles and regulation of intermediary metabolism in breast cancer whilst considering the tumour and CAAT of breast cancer as a unique Warburg's pseudo-organ. As cancer is now recognised as a systemic metabolic disease, we have paid particular attention to the cell-specific redox-metabolic reprogramming and the roles of estrogen receptors and circadian rhythms, as well as their crosstalk in the development, growth, progression, and prognosis of breast cancer.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Librarian 1 25%
Other 1 25%
Unknown 2 50%
Readers by discipline Count As %
Computer Science 1 25%
Medicine and Dentistry 1 25%
Unknown 2 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2023.
All research outputs
#22,963,239
of 25,604,262 outputs
Outputs from Febs Letters
#14,007
of 14,410 outputs
Outputs of similar age
#285,926
of 349,157 outputs
Outputs of similar age from Febs Letters
#41
of 45 outputs
Altmetric has tracked 25,604,262 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,410 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 349,157 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.