Adaptation of SARS-CoV-2 to ACE2H353K mice reveals new spike residues that drive mouse infection

Overview of attention for article published in Journal of Virology, January 2024

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@DKlemitz @BusyDrT While H353K knockin Ace2 (mACE2H353K) mice supported SARS-CoV-2 infection and replication, they exhibited minimal disease manifestations. Following 30 serial passages of ancestral SARS-CoV-2 in mACE2H353K mice, we generated and cloned…

RT @SBGrid: SBGrid's eLife paper received a citation in January from @n_schnicker of @uiowa in Journal of Virology: Adaptation of SARS-CoV-…

SBGrid's eLife paper received a citation in January from @n_schnicker of @uiowa in Journal of Virology: Adaptation of SARS-CoV-2 to ACE2H353K mice reveals new spike residues that drive mouse infection. Read more here: https://t.co/wmDAVTfUQs #SBGrid #…

@Virus_FOI_Lady @Hypothesis @KSSX18 @MariusManea_org @DMushtuk @guaro_20 @toobaffled @SabbySabs2 @dpl003 https://t.co/OHWifsvgLo.

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