Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

Overview of attention for article published in Science Translational Medicine, February 2024

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TDP-43の機能喪失に関連する新規蛋白質を同定 TDP-43の機能喪失は異常なスプライシングを引き起こし、新たなタンパク質（cryptic peptides）の産生に繋がりALS/FTDの病態に深く関与 https://t.co/Ga9Md7W39o

Open Access UCL Research: Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD https://t.co/gijoT9O3Db

RT @a_nineties: https://t.co/eG0N210rlZ "mis-spliced transcripts generate de novo proteins" interesting paper. wonder how modRNA-generated…

https://t.co/eG0N210rlZ "mis-spliced transcripts generate de novo proteins" interesting paper. wonder how modRNA-generated nonsense proteins factor into this. https://t.co/lIDMxnz9Q6

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