Effect of Coffee and Chocolate Ingestion on Clozapine Dose and on Plasma Clozapine and Norclozapine Concentrations in Clinical Practice

Overview of attention for article published in Journal of Clinical Psychopharmacology, March 2024

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New data suggest that inhibition of #clozapine metabolism by #caffeine at the doses of caffeine normally encountered in those treated with clozapine is unlikely even in male nonsmokers: https://t.co/5KbLbAOhrE #CYP1A2 #coffee #chocolate #theobromine #…

RT @JCPjournal: Effect of Coffee and Chocolate Ingestion on Clozapine Dose and on Plasma Clozapine and Norclozapine Concentrations in Clini…

Effect of Coffee and Chocolate Ingestion on Clozapine Dose and on Plasma Clozapine and Norclozapine Concentrations in Clinical Practice https://t.co/SQpXqNkiYw https://t.co/U1M96L2hrT

This study challenges the notion of dietary caffeine impacting clozapine concentrations, even among male nonsmokers. No significant effect observed on clozapine levels despite coffee and chocolate intake. 🧪☕🍫 #Clozapine #CaffeineStudy

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