Try looking up "enzyme activity and pH", also here's a...
User sapperRichter, in the Biology subreddit,
Try looking up "enzyme activity and pH", also here's a paper that talks about [ionizable side chains](http://m.jbc.org/content/28…
Protein Ionizable Groups: pK Values and Their Contribution to Protein Stability and Solubility*
Overview of attention for article published in Journal of Biological Chemistry, January 2009
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