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Nanotechnology and malaria: Evaluation of efficacy and toxicity of green nanoparticles.

Overview of attention for article published in Journal of Vector Borne Diseases, April 2024
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Title
Nanotechnology and malaria: Evaluation of efficacy and toxicity of green nanoparticles.
Published in
Journal of Vector Borne Diseases, April 2024
DOI 10.4103/jvbd.jvbd_175_23
Pubmed ID
Authors

Ana Barati, Ayan Huseynzade, Nergiz Imamova, Inji Shikhaliyeva, Sedanur Keles, Jahid Alakbarli, Buşra Akgul, Melahat Bagirova, Adil M Allahverdiyev

Abstract

Malaria is a global health problem that causes 1.5-2.7 million deaths worldwide each year. Resistance to antimalarial drugs in malaria parasites and to insecticides in vectors is one of the most serious issues in the fight against the disease. Moreover, the lack of an effective vaccine against malaria is still a major concern. Recent developments in nanotechnology have resulted in new prospects for the fight against malaria, especially by obtaining metal nanoparticles (NPs) that are less toxic, highly biocompatible, environmentally friendly, and less expensive. Numerous studies have been conducted on the synthesis of green NPs using plants and microorganisms (bacteria, fungi, algae, actinomycetes, and viruses). To our knowledge, there is no literature review that compares toxicities and antimalarial effects of some existing metallic nanoparticles revealing their advantages and disadvantages. The purpose of this review is to assess the metal NPs obtained through various green synthesis processes, to display the worth of future malaria research, and to determine future strategies. The literature review revealed that there are very limited studies on green NPs covering all stages of malaria parasites. Additionally, green metal nanoparticles have yet to be studied for their possible toxic effects on infected as well as healthy erythrocytes. Moreover, the toxicities of green metal NPs obtained from various sources differed according to concentration, size, shape, synthesis method, and surface charge, indicating the necessity of optimizing the methods used in future studies. This work has investigated the effectiveness of green metal nanoparticles synthesized from different sources against malaria, as well as their advantages and disadvantages. It was concluded that studies on the toxic properties of green nanoparticles would be very important for future stages.

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Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2024.
All research outputs
#17,554,906
of 25,738,558 outputs
Outputs from Journal of Vector Borne Diseases
#190
of 425 outputs
Outputs of similar age
#90,237
of 178,193 outputs
Outputs of similar age from Journal of Vector Borne Diseases
#1
of 1 outputs
Altmetric has tracked 25,738,558 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 425 research outputs from this source. They receive a mean Attention Score of 1.8. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,193 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them