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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pigs are highly susceptible to but do not transmit mink-derived highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b
|
|---|---|
| Published in |
Emerging Microbes & Infections, May 2024
|
| DOI | 10.1080/22221751.2024.2353292 |
| Pubmed ID | |
| Authors |
Taeyong Kwon, Jessie D. Trujillo, Mariano Carossino, Eu Lim Lyoo, Chester D. McDowell, Konner Cool, Franco S. Matias-Ferreyra, Trushar Jeevan, Igor Morozov, Natasha N. Gaudreault, Udeni B.R. Balasuriya, Richard J. Webby, Nikolaus Osterrieder, Juergen A. Richt |
| Abstract |
Rapid evolution of highly pathogenic avian influenza viruses (HPAIVs) is driven by antigenic drift but also by reassortment, which might result in robust replication in and transmission to mammals. Recently, spillover of clade 2.3.4.4b HPAIV to mammals including humans, and their transmission between mammal species has been reported. This study aimed to evaluate the pathogenicity and transmissibility of a mink-derived clade 2.3.4.4b H5N1 HPAIV isolate from Spain in pigs. Experimental infection caused interstitial pneumonia with necrotizing bronchiolitis with high titers of virus present in the lower respiratory tract and 100% seroconversion. Infected pigs shed limited amount of virus, and importantly, there was no transmission to contact pigs. Notably, critical mammalian-like mutations such as PB2-E627K and HA-Q222L emerged at low frequencies in principal-infected pigs. It is concluded that pigs are highly susceptible to infection with the mink-derived clade 2.3.4.4b H5N1 HPAIV and provide a favorable environment for HPAIV to acquire mammalian-like adaptations. |
X Demographics
The data shown below were collected from the profiles of 74 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 15 | 20% |
| Spain | 8 | 11% |
| United Kingdom | 4 | 5% |
| Netherlands | 3 | 4% |
| Mexico | 2 | 3% |
| France | 2 | 3% |
| Australia | 2 | 3% |
| Ireland | 1 | 1% |
| Philippines | 1 | 1% |
| Other | 5 | 7% |
| Unknown | 31 | 42% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 60 | 81% |
| Scientists | 11 | 15% |
| Practitioners (doctors, other healthcare professionals) | 2 | 3% |
| Science communicators (journalists, bloggers, editors) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 8 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 1 | 13% |
| Librarian | 1 | 13% |
| Student > Bachelor | 1 | 13% |
| Researcher | 1 | 13% |
| Other | 1 | 13% |
| Other | 0 | 0% |
| Unknown | 3 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 2 | 25% |
| Veterinary Science and Veterinary Medicine | 1 | 13% |
| Unspecified | 1 | 13% |
| Engineering | 1 | 13% |
| Unknown | 3 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 82. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2024.
All research outputs
#540,986
of 26,005,389 outputs
Outputs from Emerging Microbes & Infections
#74
of 1,554 outputs
Outputs of similar age
#3,577
of 157,272 outputs
Outputs of similar age from Emerging Microbes & Infections
#1
of 37 outputs
Altmetric has tracked 26,005,389 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.7. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 157,272 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.