Engineered CD47 protects T cells for enhanced antitumour immunity

RP @cyrilpedia.bsky.social: 'Although T cell depletion was greatly enhanced by CD47 blockade in our studies, our data demonstrate that macrophage phagocytosis limits the persistence of adoptively transferred T cells even in the absence of CD47–SIRPα block…

'Although T cell depletion was greatly enhanced by CD47 blockade in our studies, our data demonstrate that macrophage phagocytosis limits the persistence of adoptively transferred T cells even in the absence of CD47–SIRPα blockade' www.nature.com/articles…