ESCRT disruption provides evidence against trans-synaptic signaling via extracellular vesicles

Overview of attention for article published in Journal of Cell Biology, June 2024

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RT @interactivefly: Dresselhaus, E. C., Harris, K. P., Blanchette, C. R., Koles, K., ..., Parisi, M. J., Stewart, B. A., Mosca, T. J., Rod…

Dresselhaus, E. C., Harris, K. P., Blanchette, C. R., Koles, K., ..., Parisi, M. J., Stewart, B. A., Mosca, T. J., Rodal, A. A. (2024). ESCRT disruption provides evidence against trans-synaptic signaling via extracellular vesicles. J Cell Biol, 223(9) …

.@edresselhaus1 et al. @RodalLab show that ESCRT depletion disrupts synaptic extracellular vesicle (EV) release without affecting signaling by several EV cargoes. https://t.co/gP1DwCHd3T 📙 In our Cellular Neurobiology collection: https://t.co/Caqm4jWhlQ…

.@RodalLab (https://t.co/LeAsdmq2a9) show that for 2 different signaling molecules at the #Drosophila neuromuscular junction, #neurons release EVs most likely as a disposal mechanism—not to signal across the #synapse. Spotlight by Bostelman & Broihier…

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