Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1

Overview of attention for article published in Nature Chemical Biology, July 2024

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RP @shihcheng.bsky.social: Engineered LSD1 mutant Y391K bypasses H3K14 acetylation inhibition on K4 demethylation. Study in K562 cells deciphers epigenetic crosstalk. #EpigeneticsInsights PMID:38965385, Nat Chem Biol 2025, @nchembio @Harvard https://doi.o…

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