Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates

Overview of attention for article published in Science, August 2024

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news: 23 news outlets
blogs: 6 blogs

twitter: 54 X users
facebook: 1 Facebook page

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RT @ted_macie: @grok What do you conclude the government is doing? https://t.co/ewCehtTrWK https://t.co/UPQnZF6i8C https://t.co/ybcAAnhL…

We were inspired by @Weinberger_Lab's recent work engineering defective interfering particles (DIPs) for HIV (https://t.co/RpYR13ve58) Defective viruses, hitching a ride on wild-type HIV to replicate + spread.🤯 In our work, these DIPs emerged spontaneous…

👀Researchers successfully reduced viremia in a highly pathogenic model of HIV in rhesus macaques, providing proof of concept for a new class of single-administration antiviral therapies. Pitchai et al., @theNCI (ORIP- P51OD011092, U42OD010426) https://t.…

🙉Researchers have engineered TIPs (therapeutic interfering particles) that can conditionally replicate to reduce HIV in nonhuman primates, showing steps towards a new class of antiviral therapies. @theNCI, @DARPA, @USArmy (ORIP-P51OD011092, U42OD010426) …

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