Pseudouridine guides germline small RNA transport and epigenetic inheritance

Overview of attention for article published in Nature Structural & Molecular Biology, September 2024

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9/ We focused on the pseudouridine (Ψ) synthase PUS1. It was among the top hits, and genetic evidence implicates Ψ in RNA mobility in A. thaliana pollen: www.nature.com/articles/s41...

Pseudouridine in small RNAs guides epigenetic inheritance by aiding their transport into reproductive cells, impacting both plants and mammals. This discovery may enhance RNA therapeutic development. doi.org/g8vr6d

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